Liberia Chief Medical Officer, Dr. Catherine T. Cooper, says Liberia has recorded a total of 2,447 suspected cases of Mpox, reflecting on-going transmission across the 15 counties.
Speaking during a press conference over the weekend, Dr. Cooper said the number affects 65 out of 98 health districts. Of these suspected cases, 2,309 samples have been tested, and 1,308 cases have been laboratory confirmed, reflecting a cumulative positivity rate of 56.6%, which indicates significant on-going community transmission.
The Ministry of Health/PHIL, in collaboration with relevant partners, continues to implement enhanced surveillance, laboratory testing, and case management measures to control the spread of the infections.
According to the latest situation report (#87), 2,309 samples have been tested, of which 1,308 have been confirmed positive—reflecting a national positivity rate of 56.6%. The outbreak has affected 65 of Liberia’s 98 health districts, signaling on-going community transmission.
Currently, 148 active cases are under monitoring and clinical care in infectious disease hospitals, isolation centers, and home-based care facilities.
Montserrado County remains the hardest hit, accounting for 57% of active cases, followed by Nimba (18%), Margibi (7%), Grand Bassa (5%), and Grand Kru (4%). The remaining counties each report 2% or fewer of the total cases.
So far, 1,154 patients have recovered, while six deaths have been recorded, representing a case fatality rate (CFR) of 0.5%. Dr. Cooper noted that the relatively low death rate reflects the government’s commitment to early detection, improved case management, and community awareness campaigns.
New measures and vaccination plans include curbing transmission within the next 60 to 90 days, the Ministry of Health, NPHIL, and their partners have outlined a robust response plan. Key actions include intensified case detection, improved clinical care, refresher training for frontline health workers, and strengthened infection prevention and control measures.
Risk communication and community engagement will also be ramped up to promote safe behaviors such as frequent handwashing, early reporting of symptoms, and increased awareness of sexual transmission routes.
Beginning this month, Liberia will launch a preventive ring vaccination campaign in Montserrado and other hotspot counties. The vaccination rollout will officially start in December 2025 and continue through February 2026, targeting individuals aged 18 years and above nationwide.
In September 2025, the country received 42,720 doses of Mpox vaccines from a consortium that includes the U.S. CDC, Africa CDC, GAVI, UNICEF, and the Coalition for Epidemic Preparedness Innovations (CEPI).
The response goals (November 2025 January 2026) are to detect and investigate at least 90% of suspected Mpox cases within 24–48 hours nationwide; ensure all samples are tested with results available within 48 hours; achieve zero preventable Mpox deaths through improved ICU capacity, rapid diagnostics, and refresher training for clinicians; administer all 42,720 vaccine doses to high-risk populations by January 2026; reach 80% public awareness on safe practices and early care-seeking behavior, especially in Montserrado, Nimba, Margibi, and Grand Bassa; and reduce the national Mpox positivity rate and sustain low transmission within 90 days.
Dr. Cooper emphasized that Liberia stands at a critical turning point in its Mpox response. “Without bold actions, Mpox transmission will continue to escalate, placing lives, health systems, and communities at risk,”
